Consistent engagement with current medical literature enables clinicians to apply the latest evidence-based treatment and integrate research into clinical practice. This approach enhances patient outcomes by facilitating more effective and individualized care.

Today, we’re showcasing some of the latest hospital medicine-related articles published recently across medical journals. The articles in today’s rundown focus on sepsis, hospital-acquired pneumonia, and acute pancreatitis.

Sepsis Articles

Early Identification of a Cytokine-Low Immune Phenotype in Suspected Sepsis Using a Point-of-Care Whole-Blood TNF-α Release Assay

  • August 2026
  • Medical Sciences
  • Description: Routine biomarkers and clinical scores do not directly assess functional immune responsiveness in suspected sepsis. We evaluated whether the TNF-α Release Assay (TARA), a whole-blood LPS-induced functional assay, is associated with an early cytokine-low immune phenotype in Emergency Department (ED) patients.
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Association of Baseline and Dynamic Changes in Growth Differentiation Factor-15 Changes with Longitudinal Myocardial Function in Sepsis

  • August 2026
  • Journal of Cardiovascular Development and Disease
  • Description: Septic cardiomyopathy is a common complication of sepsis that significantly contributes to hemodynamic instability and adverse clinical outcomes. Despite increasing understanding of its pathophysiology, there is still no specific biomarker that reliably reflects myocardial function during sepsis.
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Timing of Hemoadsorption in Sepsis: Redefining Early Through Mediator-Guided Therapy

  • August 2026
  • Journal of Intensive Care
  • Description: Hemoadsorption is gaining acceptance as an adjunctive extracorporeal blood purification strategy in sepsis and septic shock; however, its clinical value remains contingent on two closely linked variables: when therapy is initiated and in whom it should be used. This review synthesizes the pathophysiological rationale, conceptual models of mediator removal, available devices, and clinical evidence for hemoadsorption in sepsis, with particular attention to patient selection.
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Hospital-Acquired Pneumonia Articles

PCR-Based Syndromic tests for Antibiotic Stewardship in Non-Ventilated Patients with Hospital-Acquired Pneumonia: A Multicentre Randomized Controlled Trial

  • July 2026
  • JAC-Antimicrobial Resistance
  • Description: To evaluate whether syndromic multiplex PCR (mPCR) with expert guidance improves antibiotic stewardship in patients with hospital-acquired pneumonia (HAP).
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Risk Warning of Systemic Immune-Inflammation Index and Coagulation Parameters for Hospital-Acquired Pneumonia in Patients with Traumatic Brain Injury

  • June 2026
  • American Journal of Translational Research
  • Description: To evaluate the predictive value of a thromboinflammatory signature integrating the Systemic Immune-Inflammation Index (SII) and routine coagulation markers for Hospital-Acquired Pneumonia (HAP) in patients with Traumatic Brain Injury (TBI).
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Can Better Oral Care Reduce Non-Ventilator Hospital-Acquired Pneumonia?

  • June 2026
  • The Lancet Infectious Diseases
  • Description: Non-ventilator hospital-acquired pneumonia (NV-HAP) is the most frequent and deadly health-care-associated infection. The Hospital Acquired Pneumonia Prevention (HAPPEN) trial, presented by Nicole M White and colleagues in The Lancet Infectious Diseases, suggests that enhanced oral care could lower NV-HAP rates.
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Acute Pancreatitis Articles

Recurrent Acute Pancreatitis Caused By A Duodenal Diverticulum: The Diagnostic Value of Secretin-Enhanced Magnetic Resonance Cholangiopancreatography

  • August 2026
  • Journal of Pediatric Gastroenterology and Nutrition
  • Description: An 11-year-old boy with a history of abdominal pain was referred for evaluation of recurrent acute pancreatitis, presenting with worsening pain and vomiting over the preceding 6 months.
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Duodenal and Pancreatic Duct Strictures After Severe Acute Pancreatitis Successfully Treated Using Fully Covered Duodenal Metal Stent-Assisted Ultrathin Gastroscopy and Duodenoscopy

  • August 2026
  • Endoscopy
  • Description: A 37-year-old patient developed duodenal and pancreatic duct strictures secondary to severe acute pancreatitis. Despite conservative therapy, resumption of oral intake repeatedly triggered recurrent pancreatitis with elevated amylase levels, abdominal pain, distension, and vomiting.
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Severe Acute Pancreatitis and Toxic Hepatitis After Solitary Dietary Supplement Ingestion: A Case Report

  • August 2026
  • Medicine
  • Description: Although many products have been approved for weight loss, their efficacy remains debatable owing to the insufficient scientific evidence in the relevant literature. Furthermore, because of the limited clinical data and research, the adverse effects of these products remain unelucidated.
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