Guideline Video

Guideline Resources

  • Early Detection of Prostate Cancer
  • American Urological Association & Society of Urologic Oncology
  • February 25th, 2026
  • Summary
  • Full-text

Video Transcription

Just published February 25th, 2026, the American Urological Association and Society of Urologic Oncology’s newest guideline update on Early Detection of Prostate Cancer.

The recommendations in this guideline discuss early detection of prostate cancer and provide a framework to facilitate clinical decision-making in the implementation of prostate cancer screening and follow-up.

In today’s rapid update, we’ll just be going over the key changes from this 2026 guideline. For the full guideline, make sure to check it out on guidelinecentral.com

Let’s get started. 

For the section on Initial Biopsy,

Clinicians may use MRI prior to initial biopsy to increase the detection of Grade Group 2+ prostate cancer. This recommendation was upgraded from Evidence Level: Grade B to Grade A.   

On to the section on Repeat Biopsy,

In patients with atypical small acinar proliferation, clinicians should perform additional testing, which may include repeat biopsy. This recommendation was upgraded from Expert Opinion to Moderate Recommendation; Evidence Level: Grade C.

And last for the section on Biopsy Technique,

Clinicians may use either a transrectal or transperineal biopsy route when performing a biopsy. This recommendation was upgraded from Evidence Level: Grade C to Grade B. 

And there you have it. Make sure to check out the full guideline from the American Urological Association and Society of Urologic Oncology and other related clinical decision support tools at guidelinecentral.com. 

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