Management of Chronic Kidney Disease in Patients Infected With HIV

IDSA recommends monitoring creatinine-based estimated glomerular filtration rate (GFR) when antiretroviral therapy (ART) is initiated or changed, and at least twice yearly in stable HIV-infected patients using the same estimation method to track trends over time. More frequent monitoring may be appropriate for patients with additional kidney disease risk factors. (SR, L)

IDSA recommends that clinicians prescribe ART and encourage persistence with therapy in HIV-infected patients who have CKD or ESRD, since ART reduces mortality but is underused in this patient population. (SR, M)