Chronic Kidney Disease in HIV-Infected Patients

Publication Date: September 24, 2014

Key Points

Key Points

  • The risk of chronic kidney disease (CKD) is increased in individuals infected with human immunodeficiency virus (HIV) compared with the general population.
  • In African Americans, HIV infection imparts a risk for end-stage renal disease (ESRD) that is of similar magnitude to that of diabetes.
  • -infected patients, including direct effects by HIVA constellation of potential factors contributes to excess kidney disease in HIV-infected patients, including direct effects by HIV infection, HIV-associated immune activation, drug toxicity, coinfection with hepatitis C virus, and a high prevalence of traditional kidney disease risk factors.

Diagnosis

...gnosis

...onitorin...

...recommends monitoring creatinine-based...

...sts monitoring kidney damage with urinal...


...luation

...that the evaluation of new-onset or newly disco...

...ommends that HIV-infected patients with kidney...

...IDSA recommends establishing permanent dialys...

...ible, IDSA recommends avoiding the use of periph...

Figure 1. Chronic Kidney Disease Classification...

...able 1. Classification of Albuminuria and...

...isk Factors for CKD and ESRD: Data From St...

...Laboratory Indicators of Proximal Tubular...


Treatment

...reatment

...anagemen...

...SA recommends that clinicians presc...

IDSA recommends that clinicians use either the C...

...A recommends that patients with biopsy-confir...

...patients infected with HIV who have a...

...r-treated patients who experience a confirmed G...


Cardiovascular...

...SA recommends using angiotensin-converting en...

...ends that HIV-infected individuals with pre-ESR...

...hat clinicians consider prescribing...


Blood Press...

...recommends a target blood pressure of...

...a target blood pressure of 30-300 mg/day or equi...


Corticostero...

...gests that clinicians consider corticosteroids as...


...dney Transplantati...

...commends that HIV providers assess patient...

...mends that HIV providers assess patien...


Children and Adolescents with HIV

...dren and Adolescents with...

...creening

...s, IDSA recommends that children and adol...

...ggests avoiding tenofovir as part of firs...


...atment...

...that children and adolescents with...

...using ACE inhibitors or ARBs to treat proteinuri...

...suggests that corticosteroids NOT be used i...

...g of Antiretroviral Drugs for HIV-Infected Adul...