Consistent engagement with current medical literature enables clinicians to apply the latest evidence-based treatment and integrate research into clinical practice. This approach enhances patient outcomes by facilitating more effective and individualized care.

Today, we’re showcasing some recently published allergy and immunology-related articles. The topics in today’s rundown focus on drug allergies and food allergies. Some article descriptions were edited for clarity and brevity.

Drug Allergies

Implementing an Evidence-Based Guideline to Improve Perioperative Antimicrobial Prophylaxis Quality Among Patients With Penicillin Allergy Labels

  • Mayo Clinic Proceedings
  • June 2026
  • Description: An interdisciplinary quality improvement project was conducted in a large, multiregion health care system in the United States to promote cefazolin for surgical antimicrobial prophylaxis among  patients with penicillin allergy labels.
  • Summary
  • Full Text

Diagnosing NSAID-Hypersensitivity/Allergy and NSAID-Exacerbated or Induced Food Allergy Phenotypes in Children and Adolescents

  • The Journal of Allergy and Clinical Immunology: In Practice
  • June 2026
  • Description: Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used in children. Hypersensitivity reactions (HRs) to NSAIDs represent a diagnostic challenge, particularly because NSAIDs may act as aggravating factors or cofactors as in two phenotypes recently named NSAID-exacerbated food allergy (NEFA) and NSAID-induced food allergy (NIFA).
  • Summary
  • Full Text

The Role of In Vivo, In Vitro and Pharmacogenomic Diagnostic Approaches to Sulfonamide Allergy

  • The Journal of Allergy and Clinical Immunology
  • May 2026
  • Description: Sulfonamide antibiotic allergy labels may lead to inappropriate avoidance of other “sulfur”-containing medications, because cross-reactivity is unlikely between antibiotic and nonantimicrobial sulfonamides. In this review, [the researchers] discuss the typical presentation of sulfonamide antibiotic hypersensitivity reactions.
  • Summary
  • Full Text

Evaluating Penicillin Allergy Clinical Decision-Making Tools to Enhance Penicillin Allergy Delabeling

  • The Journal of Allergy and Clinical Immunology
  • April 2026
  • Description: Patient-reported penicillin allergy is associated with adverse outcomes. [The researchers] aimed to evaluate clinical decision-making tools used to risk-stratify reported penicillin allergies for delabeling.
  • Summary
  • Full Text
Food Allergy

Fear and Picky Eating‐Related ARFID Behaviors in Children with Food Allergy

  • Pediatric Allergy and Immunology
  • July 2026
  • Description: Food allergy is a chronic condition with psychosocial consequences for both children and their families. Strict elimination diets and fear of adverse reactions may contribute to maladaptive coping including behaviors avoidant/restrictive food intake disorder (ARFID)-related eating patterns. Therefore, this study aimed to compare ARFID-related eating behavior scores between children with food allergy and healthy controls and to identify the affected domains.
  • Summary
  • Full Text

Seeds, Spices-Not Always so Nice: A Report on the FARE (Food Allergy Research & Education) Patient Registry

  • The Journal of Allergy and Clinical Immunology
  • June 2026
  • Description: An estimated 33 million Americans have food allergy. Allergists are seeing an increasing number of patients for allergies to foods once thought to be rare causes of the disease.
  • Summary
  • Full Text

Biologic-Assisted Immunotherapy for Pediatric Food Allergy: A Systematic Review

  • Frontiers in Allergy
  • June 2026
  • Description: Food allergies affect up to 8% of children and are a major cause of anaphylaxis, reduced quality of life, and healthcare use. Oral immunotherapy (OIT) can induce desensitization but is limited by adverse reactions, tolerability challenges, and variable long-term outcomes. Emerging biologic therapies- particularly omalizumab and dupilumab- may improve the safety and efficiency of desensitization when used alone or with immunotherapy.
  • Summary
  • Full Text

Don’t miss our other allergy and immunology-related content and sign up for alerts and stay informed on the latest published articles and guidelines.