Consistent engagement with current medical literature enables clinicians to apply the latest evidence-based treatment and integrate research into clinical practice. This approach enhances patient outcomes by facilitating more effective and individualized care.

Today, we’re showcasing some of the latest nephrology-related articles published recently across medical journals. The topics in today’s rundown include articles on diabetic kidney disease, nephrotic syndrome, and hypertensive nephropathy.

Diabetic Kidney Disease Articles

Exploring the Potential Targets and Mechanisms of Artemisinin in the Treatment of Diabetic Kidney Disease Using Network Pharmacology and Molecular Docking

  • Functional & Integrative Genomics
  • June 2026
  • Description: Diabetic kidney disease is a secondary glomerular disease caused by diabetes, and its incidence is increasing annually. Artemisinin is an organic compound with multiple pharmacological effects. This study aims to investigate the potential therapeutic effects of artemisinin on diabetic kidney disease and its molecular mechanisms.
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Adding Finerenone to SGLT2 Inhibitors and Long-Term Kidney Outcomes in Diabetic Kidney Disease

  • Diabetes, Obesity & Metabolism
  • May 2026
  • Description: Despite treatment with renin–angiotensin system inhibitors and sodium–glucose cotransporter 2 inhibitors (SGLT2is), diabetic kidney disease continues to exhibit substantial residual renal risk. The renoprotective effects of adding finerenone to dual therapy remain incompletely characterized.
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Molecular Mechanisms and Therapeutic Strategies of Glomerular Cell Senescence in Diabetic Kidney Disease: From Heterogeneity to Precision Intervention

  • Cellular and Molecular Life Sciences
  • May 2026
  • Description: This manuscript explores the core mechanisms regulating glomerular cell senescence and their impact on renal filtration barrier injury, inflammation, and glomerulosclerosis, with a specific focus on the senescent characteristics and interactions of different types of glomerular cells. It also discusses senescence-related diagnostic biomarkers and epigenetic clocks.
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Nephrotic Syndrome

Biallelic Pathogenic variants in FLNB are Associated with Paediatric Steroid-Resistant Nephrotic Syndrome via Podocyte Cytoskeletal Dysfunction

  • Journal of Medical Genetics
  • May 2026
  • Description: Steroid-resistant nephrotic syndrome (SRNS) is a severe paediatric kidney disease and a leading cause of end-stage kidney disease in children, with a high genetic contribution. While over 80 monogenic causes of SRNS have been identified, a significant proportion of affected patients still lack a clear genetic diagnosis, indicating that additional causative genes remain to be discovered.
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Medication-related nephrotic syndrome: a real-world study from 2004 to 2024 based on the Food and Drug Administration Adverse Event Reporting System

  • Therapeutic Advances in Drug Safety
  • May 2026
  • Description: Nephrotic syndrome is a clinical syndrome caused by glomerular injury. Medication-related nephrotic syndrome (MRNS) has become an important focus of pharmacovigilance. However, there is currently a lack of real-world studies on MRNS in large populations.
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Association Between Microscopic Hematuria and Proteinuria Remission in Adult Nephrotic Syndrome

  • Kidney Medicine
  • March 2026
  • Description: Although the prognostic significance of hematuria has been established in various kidney diseases, few studies have investigated its role in nephrotic syndrome. This study aimed to characterize the prevalence and severity of microscopic hematuria at diagnosis and examine its association with proteinuria remission in adults with nephrotic syndrome.
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Hypertensive Nephropathy Articles

The Role of Non-Coding RNA in the Pathogenesis of Hypertensive Nephropathy

  • Cells
  • April 2026
  • Description: Hypertensive nephropathy is a leading cause of chronic kidney disease and end-stage renal disease worldwide and results from the long-term effects of hypertension on renal structure and function. The pathogenesis of hypertensive nephropathy is complex and involves haemodynamic disturbances, renal vascular injury, oxidative stress, chronic inflammation, and progressive interstitial fibrosis. This review summarises the current understanding of the molecular mechanisms underlying hypertensive nephropathy, with particular emphasis on the roles of oxidative stress, activation of the renin–angiotensin–aldosterone system, transforming growth factor beta signalling, and inflammatory and fibrogenic pathways.
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Advancing Precision Medicine for Hypertensive Nephropathy: A Novel Prognostic Model Incorporating Pathological Indicators

  • Kidney & Blood Pressure Research
  • March 2026
  • Description: This study aimed to assess the long-term renal prognosis of patients with hypertensive nephropathy diagnosed through renal biopsy, utilizing the random survival forest algorithm.
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