Staying current with evolving medical research is essential for delivering high-quality, evidence-based care, particularly when it comes to neurological health. Advances in migraine, epilepsy, and stroke management continually refine diagnostic and therapeutic approaches. Ongoing engagement with the latest research allows clinicians to implement effective interventions safely and incorporate innovations that improve patient outcomes and overall health.

Today, we’re showcasing some of the most recently published neurology-related articles from medical journals. These neurology articles focus on migraines, epilepsy, and stroke. The articles are separated by topic and some of their associated descriptions were edited for clarity and brevity.

Migraine Topics

The Promise of Machine Learning in Predicting Migraine Attacks

  • Cephalalgia: An International Journal of Headache, November 2025
  • Description: This narrative review establishes the current state of the art of machine learning approaches for prediction of migraine attacks.
  • Summary
  • Full Text

Magnesium Supplementation for Migraine Prophylaxis

  • The Cochrane Database of Systematic Reviews, November 2025
  • Description: This study evaluated the benefits and harms of magnesium supplementation for preventing episodic or chronic migraine in children and adults compared to usual pharmacological treatment or placebo.
  • Summary
  • Full Text

Vitamin D Deficiency and Supplementation in Migraine: A Scoping Review of Clinical Efficacy, Evidence Gaps, and Research Priorities

  • Annals of Indian Academy of Neurology, November 2025
  • Description: This scoping review aimed to map global vitamin D deficiency prevalence across migraine subtypes and geographic regions, synthesize clinical correlations between vitamin D status and migraine characteristics, and explore heterogeneity in therapeutic evidence across paediatric, chronic, and refractory migraine subgroups.
  • Summary
  • Full Text

The Effect of Treatment Onset Time on Acute Efficacy in Migraine Patients Treating with Remote Electrical Neuromodulation (REN)

  • Cephalalgia: An International Journal of Headache, October 2025
  • Description: A real-world evidence study on migraine patients who were treated with remote electrical neuromodulation.
  • Summary
  • Full Text
Epilepsy Topics

Refractory Focal Epilepsy Evolving into Lennox-Gastaut Syndrome-like

  • Journal of Neurology, November 2025
  • Description: Patients with focal epilepsy may over time experience a significantly unfavorable progression, developing an electroclinical profile that meets some or all criteria for Lennox-Gastaut syndrome (LGS). This study aimed to describe the electroclinical characteristics of these patients, whom [the researchers] referred to as patients with LGS-like, and to determine their common and distinguishing features compared to classical LGS.
  • Summary
  • Full Text

Technical Neurosurgical Aspects of Pediatric Epilepsy Surgery Including Resections and Disconnections

  • Pediatric Neurosurgery, November 2025
  • Description: Epilepsy remains one of the most common neurological disorders in children, with approximately one-third of patients developing drug-resistant epilepsy that may require surgical intervention. This review outlines the technical neurosurgical aspects of pediatric epilepsy surgery, focusing on resective and disconnection procedures.
  • Summary
  • Full Text

Seizure Outcomes of Laser Interstitial Thermal Therapy (LITT) for Drug-Resistant Extratemporal Epilepsy

  • Epileptic Disorders, November 2025
  • Description: Magnetic resonance image-guided laser interstitial thermal therapy (LITT) is a minimally invasive alternative to surgical resection for the treatment of drug-resistant epilepsy. Seizures arising outside of the temporal lobe can be difficult to treat due to the heterogeneity of anatomical locations and underlying pathologies. The effectiveness of LITT ablations for extratemporal lobe epilepsy is not well established.
  • Summary
  • Full Text
Stroke Topics

Improving the Interface for Information Transfer in Acute Stroke Care: A Mixed-Methods Process Evaluation of the Emergency Use Case Within the CAEHR Project

  • BMJ Open, November 2025
  • Description: Prehospital notification by emergency medical services (EMS) can activate hospital resources before the patient arrives, which has been shown to improve in-hospital care for stroke patients. Optimising prehospital and handover processes in stroke care requires considering end-user perspectives to enhance acceptance and effectiveness of the developed solutions. The aim of this study was to identify current barriers in the preclinical-clinical phase of stroke care.
  • Summary
  • Full Text

Incidence and Outcomes of Hospitalized Acute Ischemic Stroke Patients with Subsequent ST-segment-elevation Myocardial Infarction

  • Frontiers in Cardiovascular Medicine, October 2025
  • Description: Patients admitted with acute ischemic stroke (AIS) may experience accompanying acute ST-Segment myocardial infarction after AIS. The cardiovascular risks, incidence, complications, and outcomes of acute STEMI in patients hospitalized with AIS remains underexplored.
  • Summary
  • Full Text

The Association of Life’s Essential 8 with Risk of Stroke: The EPIC-NL Prospective Cohort Study

  • Nutrition, Metabolism, and Cardiovascular Diseases (NMCD), October 2025
  • Description: The American Heart Association (AHA) released the Life's Essential 8 (LE8) metrics for cardiovascular health promotion. This study aimed to identify the association between LE8 and the risk of total, ischemic, and hemorrhagic stroke.
  • Summary
  • Full Text

Look forward to more journal-focused topics in the coming weeks. Sign up for alerts and stay informed on the latest published articles and guidelines.

Copyright © 2025 Guideline Central, all rights reserved.