Guideline Central Blog


Guidelines+ Trials Spotlight - Hemochromatosis

Advances in Hemochromatosis – Guidelines+ Trials Rundown

Today, we will explore the latest research and clinical trials focused on the management of hemochromatosis. The following list has been carefully curated by evaluating ongoing trials related to hemochromatosis in the United States. Please note that the dates provided are approximate and may be subject to change. The list primarily includes studies with results […]

Best Uses of AI LLMs in Guidelines Development

Top Ideas & Best Uses of AI / LLMs in Clinical Practice Guidelines Development

This article will examine a number of ideas and top suggestions for incorporating LLMs and AI, including Chatbots like GPT4 or Llama, into your clinical practice guidelines development process and workflows. As I’m sure you’ve heard, AI is improving and expanding rapidly, and that this is a moving target, so we’ll build upon this series […]

What's Changed & Predictions Age-Related Macular Degeneration

Age-Related Macular Degeneration Guidelines: What’s Changed Since & Guidelines Prediction Series

As the leading cause of irreversible blindness in adults 60 years of age and older, age-related macular degeneration (AMD) is a prevalent eye condition marked by central vision loss that impacts nearly 20 million individuals in the US. Despite its prevalence, afflicting approximately 1 in every 8 individuals above 60 years of age, there are […]

Guidelines Spotlight - Stimulant Use Disorder

Stimulant Use Disorder – Guidelines Spotlight

The American Society of Addiction Medicine (ASAM) and the American Academy of Addiction Psychiatry (AAAP) collaborated to develop the Clinical Practice Guideline on the Management of Stimulant Use Disorder (referred to as the Guideline). It was published on November 8, 2023. The Guideline aims to provide evidence-based strategies and clinically informed standards of care for […]

Guidelines + Journal Rundown Pediatrics

Top Pediatric Articles July 2024 – Guidelines+ Journals

In this post, we will be taking a closer look at some of the most popular pediatric-related articles recently published across medical journals. Infant Deaths After Texas’ 2021 Ban on Abortion in Early Pregnancy Global Prevalence of Overweight and Obesity in Children and Adolescents: A Systematic Review and Meta-Analysis Screening Accuracy of BMI for Adiposity […]

ACOG Pregnancy & Postpartum Algorithms

New Pregnancy and Postpartum Algorithms Published by ACOG

The American College of Obstetricians and Gynecologists (ACOG) and the Centers for Disease Control and Prevention (CDC) have collaborated on a multiyear initiative entitled “Identifying and Managing Obstetric Emergencies in Nonobstetric Settings.” This initiative addresses pregnancy-related emergencies and complications such as cardiomyopathy, preeclampsia, eclampsia, and stroke, as well as mental health conditions that can pose […]

AGA’s Ulcerative Colitis Guideline is Now Open for Public Comment

The American Gastroenterological Association (AGA) has announced that their latest guideline, “The AGA Living Guideline: Pharmacological Management of Moderate-To-Severe Ulcerative Colitis,” is now open for public comment. This guideline, aimed at supporting practitioners in the pharmacological management of moderate-to-severe ulcerative colitis (UC), features 14 recommendations designed to guide therapy decisions with a patient-centered approach. Referred […]

Guidelines Side-By-Side Psoriatic Arthritis

Analyzing Guidelines for Psoriatic Arthritis (PsA) – Guidelines Side-By-Side

Psoriatic arthritis (PsA) is a chronic, immune-mediated inflammatory arthritis that occurs most commonly in some people with psoriasis, a skin condition characterized by red, scaly patches. Research suggests that approximately 20-30% of people with psoriasis also develop PsA, with the majority of patient’s presenting with skin-related disease that precedes the onset of arthritis symptomatology, though […]

Guidelines Spotlight - Vitamin D for the Prevention of Disease

Vitamin D for the Prevention of Disease: Guidelines Spotlight

The Endocrine Society unveiled its latest guideline, “Vitamin D for the Prevention of Disease,” on June 3rd, 2024. This evidence-based guideline aims to establish clinical guidelines for the use of vitamin D to lower the risk of disease in individuals without established indications for vitamin D treatment or 25(OH)D testing. Recognized for its vital role […]

Guidelines + Trials Rundown - Juvenile Arthritis

Advances in Juvenile Arthritis – Guidelines+ Trials Rundown

We’re going to take a look at the ongoing studies and clinical trials specific to juvenile arthritis. The below list was curated by assessing the ongoing Phase 3 trials for juvenile arthritis that are based in the United States. The dates provided are estimates, and subject to change. The list is primarily studies that have […]

Guidelines Side-By-Side Migraine & Headache

A Comparative Analysis of Migraine & Headache Management Guidelines – National Migraine & Headache Awareness Month

National Migraine and Headache Awareness Month, observed in June, is an annual event that highlights the importance of utilizing evidence-based strategies when crafting patient-centered treatment plans for individuals grappling with headaches and migraines. With headaches ranking the 5th most common reason for emergency department visits, it is no surprise that the CDC estimates migraine disorder […]

ISTH 2024 Recap

ISTH 2024 Conference Recap: Venous Thromboembolism (VTE)

The International Society on Thrombosis and Haemostasis held its annual conference (ISTH 2024) in Bangkok, Thailand from June 22-26th. It is the premier global organization dedicated to advancing the understanding, prevention, diagnosis, and treatment of conditions related to thrombosis and hemostasis. During ISTH 2024, groundbreaking research on venous thromboembolism (VTE) was presented, showcasing the latest […]

Guidelines Spotlight - Epilepsy in Women

Teratogenesis, Perinatal, and Neurodevelopmental Outcomes After in Utero Exposure to Antiseizure Medication: Guidelines Spotlight

A focused guideline update “Teratogenesis, Perinatal, and Neurodevelopmental Outcomes After in Utero Exposure to Antiseizure Medication” was released by the American Academy of Neurology (AAN), the American Epilepsy Society (AES), and the Society for Maternal-Fetal Medicine (SMFM) on May 15, 2024. The new guideline updates the previous 2009 guideline for “Management Issues for Women with […]

Guidelines Side-By-Side IBS

Comparing AGA and ACG Guidelines for Irritable Bowel Syndrome (IBS) – Guidelines Side-By-Side

This week’s Guidelines Side-By-Side Series will compare the irritable bowel syndrome (IBS) guidelines from the two prominent GI-related associations in the United States – AGA and ACG. Below is an overview of the three guidelines that will be compared side-by-side. The AGA guidelines, while technically two separate documents, were published together at the same time. […]

Guidelines+ Journal Rundown Orthopedics

Top Orthopedics and Sports Medicine Articles June 2024 – Guidelines+ Journals

In this post, we will be taking a closer look at some of the most popular orthopedics and sports medicine-related articles recently published across medical journals. Beneficial effects of exercise, testosterone, vitamin D, calcium and protein in older men-A randomized clinical trial Activity-Dependent Compensation at the Hip and Ankle at 8 Years After the Reconstruction […]

Guidelines+ Trials Rundown - Gout

Gout in Adults – Guidelines+ Trials Rundown

Today we’re going to look at the ongoing studies and clinical trials specific to gout in adults. The below list was curated by assessing the ongoing Phase 3 trials for gout, specific for adults, and based in the United States. The dates provided are estimates, and subject to change. The list is primarily studies that […]

SVSVAM 2024 Recap

VAM24 Conference Recap – The Latest Research on Aortic Disease

The 2024 Vascular Annual Meeting (VAM24) took place from June 19-22 in Chicago, Illinois, serving as the Society of Vascular Surgery’s (SVS) premier event. This meeting provided a plethora of valuable scientific content tailored to meet the needs of every member of the vascular care team. A key focus of VAM24 was aortic disease, encompassing […]

Upadacitinib (Rinvoq / AbbVie) and Current Clinical Guidelines – Guidelines+ Monographs

In this edition of our Guidelines+ Monographs Series, we will be taking a look at AbbVie’s medication Upadacitinib, brand name Rinvoq. Initially approved in 2019 Rinvoq is a Janus kinase (JAK) inhibitor used to treat a variety of conditions, including rheumatoid arthritis, psoriatic arthritis, atopic dermatitis, ulcerative colitis, Crohn’s disease, ankylosing spondylitis, and non-radiographic axial […]

Guidelines Rundown Multiple Myeloma

What’s New in Multiple Myeloma Guidelines – Guidelines Rundown

Multiple Myeloma, also known as Myeloma or Plasma Cell Myeloma, is a type of cancer that affects plasma cells, which are responsible for producing antibodies to protect against infections. This disease can present in various ways, ranging from a slow-developing form with minimal protein abnormalities and few malignant cells to a rapidly progressing and life-threatening […]

What's Changed & Predictions Eosinophilic Esophagitis (EoE)

Eosinophilic Esophagitis Guidelines: What’s Changed Since+ Guidelines Prediction Series

EoE (eosinophilic esophagitis) is a chronic, immune-mediated condition characterized by mucosal inflammation and esophageal dysfunction as the result of an eosinophilic-predominant immunogenic reaction. EoE, with onset typically secondary to genetic predisposition or antigen-triggered in etiology, results in damage to the esophagus that symptomatically can present as dysphagia, odynophagia, episodes of choking episodes, or can be […]

Guidelines Spotlight - Survivorship Care for People Affected by Advanced or Metastatic Cancer

Survivorship Care for People Affected by Advanced or Metastatic Cancer: Guideline Spotlight

The Multinational Association for Supportive Care in Cancer and the American Society of Clinical Oncology (MASCC-ASCO) have recently published new guidelines entitled “Survivorship Care for Individuals Affected by Advanced or Metastatic Cancer,” on April 29, 2024. These guidelines provide comprehensive and evidence-based recommendations intended to improve the quality of life and optimize the outcomes for […]

Guidelines+ Journal Rundown Pulmonology

Top Pulmonology Articles June 2024 – Guidelines+ Journals

In this post, we will be taking a closer look at some of the most popular pulmonology-related articles recently published across medical journals. Remission in asthma Electrocardiographic Abnormalities and Their Association with Outcomes in Randomized Clinical Trials of Pulmonary Arterial Hypertension DLco and echocardiographic parameters in identifying mild pulmonary hypertension in the EUSTAR cohort of […]

Clinical Guidelines Implementation Strategy - Step 6 & 7: Measure & Evaluate, Change, Optimize & Repeat

Guideline Implementation Series: Final Steps (6-7) – Measure and Evaluate Change, Optimize, and Rinse and Repeat!

At this point you’ve not only planned your implementation initiative as discussed in our previous article, but you’ve also begun to actually implement it. A very critical (and often overlooked) step is to measure and evaluate your change, with a goal of optimization and iterative refinement and improvements. Also, to communicate your findings internally in […]