The American Urological Association (AUA) stands as the leading urologic association, offering invaluable support to the global urologic community and its 23,000 members. Their mission is to advance the highest standards of urological clinical care through education, research, and the development of healthcare policies. AUA’s Clinical Practice Guidelines provide evidence-based guidance with a clear scope […]
In the latest edition of the Guidelines International Series, we delve into the most recent guidelines published by the esteemed European Society of Cardiology (ESC). As a global leader in the field of cardiovascular medicine, the ESC brings together a community of over 100,000 scientists, clinicians, nurses, and allied professionals dedicated to advancing best practices […]
Ovarian cancer, the 5th leading cause of cancer deaths in the U.S., is one of the deadliest gynecologic malignancies due to its mild early symptoms, often leading to late detection. This edition of our Guidelines+ Monograph series explores niraparib (brand name Zejula) from GlaxoSmithKline (GSK), a once-daily oral (PO) PARP inhibitor. It’s FDA-approved as a […]
Hemophilia A and B, the most common severe hereditary bleeding disorders, arise from deficiencies in factor VIII and factor IX, respectively. These conditions result in prolonged bleeding episodes, which can occur spontaneously or with minimal trauma, depending on the level of factor activity. Apart from treating acute bleeding, prophylaxis is a key strategy in hemophilia […]
The Centre for Research Excellence in Women’s Health in Reproductive Life (CRE WHiRL) collaborated with esteemed organizations such as the American Society for Reproductive Medicine (ASRM), Endocrine Society, European Society of Endocrinology (ESE), and European Society of Human Reproduction and Embryology (ESHRE), while collaborating with other professional societies. Together, they have enhanced the 2018 International […]
This National Sickle Cell Awareness Month, our Guidelines Rundown Series continues with a new article that delves into the topic of sickle cell disease. Multiple societies have released comprehensive guidelines to provide guidance and support for clinical decision-making in the prevention, diagnosis, and management of sickle cell disease in both adults and children. In this […]
The opioid crisis continues to be a major public health issue, with overdose rates still rising in many areas, particularly due to the increasing prevalence of synthetic opioids like fentanyl. This edition of our Guidelines+ Monograph series will be dedicated to International Overdose Awareness Day, a day on August 31st of each year dedicated to […]
The Food and Drug Administration (FDA) protects public health by guaranteeing the safety, effectiveness, and security of pharmaceuticals and medical devices. The Prescription Drug User Fee Act (PDUFA) date marks the deadline by which the FDA must complete its review of drug applications. Occasionally, an advisory committee (AdCom) meeting is convened to assess the drug […]
Updated Content from the 2019 ECDP Patients Hospitalized with Heart Failure In August 2024, the American College of Cardiology (ACC) published a focused update on the Clinical Assessment, Management, and Trajectory of Patients Hospitalized With Heart Failure that harmonizes their 2019 ACC ECDP with the 2022 ACC/AHA Heart Failure guidelines to provide updated recommendations regarding […]
Patients with uncomplicated urinary tract infections (UTIs) do not have any structural abnormalities in their urinary tract or comorbidities such as diabetes, an immunocompromised state, recent urologic surgery, or pregnancy. An uncomplicated UTI is also referred to as cystitis or a lower tract UTI. It is estimated that approximately half of all women will experience […]
In this new series, we bring you the latest news stories that illustrate the complex intersections between healthcare and the legal system. From medical malpractice and patient rights to bioethics and regulatory challenges, we delve into how these two critical fields collide and interact. Join us as we navigate the multifaceted relationship between medicine and […]
The American Society of Clinical Oncology (ASCO) has announced that the following guidelines, “Systemic Therapy in Men with Metastatic Castration-Resistant Prostate Cancer: ASCO Guideline Update” and “Germline and Somatic Genomic Testing in Metastatic Prostate Cancer: ASCO Guideline” are now open for public comment. The Metastatic Castration-Resistant Prostate Cancer Guideline, is an update to ASCO’s 2014 […]
In this post, we will be taking a closer look at some of the most popular oncology / hematology oncology-related articles recently published across medical journals. Phase III KEYNOTE-789 Study of Pemetrexed and Platinum With or Without Pembrolizumab for Tyrosine Kinase Inhibitor‒Resistant, EGFR–Mutant, Metastatic Nonsquamous Non–Small Cell Lung Cancer First-Line Nivolumab Plus Relatlimab Versus Nivolumab […]
The American Gastroenterological Association (AGA) has announced that their latest guideline, the “AGA Guideline on the Prevention and Treatment of Hepatitis B Virus Reactivation in Immunosuppressed Individuals” is now open for public comment. This guideline, aimed at educating and providing guidance to frontline health practitioners on the prevention and management of Hepatitis B virus reactivation […]
In our latest installment of the Guidelines International Series, we will be looking at the latest guidelines from the International Society on Thrombosis and Haemostasis (ISTH). As the leading global organization in the field of bleeding and clotting disorders, ISTH plays a pivotal role in offering healthcare professionals and researchers worldwide with invaluable educational resources, […]
Gout is a common medical condition characterized by the accumulation of monosodium urate (MSU) monohydrate crystals in the tissues, often resulting in painful flares that can last for one to two weeks. According to the National Institutes of Health (NIH), gout is more prevalent in men than in women and typically presents in middle age. […]
The American Academy of Ophthalmology (AAO) is the largest association of eye physicians and surgeons globally. Their mission is to protect vision and enhance quality of life by establishing the benchmarks for ophthalmic education and championing the interests of patients and the general public. AAO regularly releases Preferred Practice Pattern® guidelines (PPP) aimed at defining […]
Affecting more than one-third of adults in the US, obesity remains a pressing health challenge for both providers and patients, conferring significant risk for comorbidities such as type 2 diabetes, obstructive sleep apnea, and cardiovascular disease. While lifestyle modifications and medical therapies, including anti-obesity medications (AOM), can be effective for some, they often fall short […]
In this edition of our Guidelines Monographs Series, we will be taking a look at AstraZeneca’s medication dapagliflozin, brand name Farxiga. Initially approved in 2014, Farxiga is a sodium-glucose cotransporter 2 (SGLT2) inhibitor, provided to individuals with diabetes, heart disease, or kidney disease to improve their outcomes. This Guidelines+ Monograph will take a deeper dive […]
On July 2, 2024, the US Food and Drug Administration (FDA) granted approval for Eli Lilly’s Kisunla (donanemab-azbt) injection for the treatment of Alzheimer’s disease. This treatment is recommended for patients in the early stages of the disease, specifically those with mild cognitive impairment or mild dementia, as demonstrated in the clinical trials. Kisunla marks […]
High cholesterol, also known as hyperlipidemia, affects millions of individuals in the United States (US). This condition can lead to serious health issues, such as an increased risk of heart disease and stroke. Globally, approximately one-third of cases of ischaemic heart disease are linked to high cholesterol levels. Elevated total cholesterol is a significant contributor […]
As we prepare for the National Immunization Awareness Month 2024 and upcoming autumn season, we will be conducting a thorough review of the United States Immunization Schedules for both Adults and Children. These crucial recommendations are released annually by the Centers for Disease Control and Prevention (CDC). They offer essential guidance on the recommended schedules […]
In this post, we will be taking a closer look at some of the most popular sleep medicine-related articles recently published across medical journals. Longer-term effect of physical activity intervention on sleep quality: a secondary analysis of cluster randomized controlled trial Delayed school start time is associated with better sleep, mental health, and life satisfaction […]
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by systemic inflammation primarily affecting the synovial joints. This condition arises from an aberrant immune response targeting the synovium, leading to persistent inflammation, joint damage, and potential systemic manifestations. If left untreated, RA can cause significant damage to the joints and surrounding tissues, potentially leading to […]
The American Academy of Neurology (AAN) has announced that their latest guideline, “Pharmacologic Treatment for Migraine Prevention in Adults Practice Guideline Update: Report of the AAN Guidelines Subcommittee,” is now open for public comment. This practice guideline offers updated evidence-based conclusions and recommendations on the use of pharmacologic migraine prevention in adults. The primary objective […]