Guideline Central Blog

Clinical Practice Guidelines

WHO Int'l Guidelines

The World Health Organization (WHO) – Guidelines International Series

In the latest installment of our Guidelines International Series, we will be delving into the latest guidelines from the World Health Organization (WHO). Established in 1948, WHO is a specialized agency of the United Nations (UN) that facilitates collaboration between nations, partners, and individuals to advance global health, ensure global security, and support marginalized populations. […]

Anesthesiology: Guidelines + Journals Rundown

Anesthesiology – Guidelines+ Journals Rundown

In this post, we will be taking a closer look at some of the most popular anesthesiology-related articles recently published across medical journals. Increasing Sweep Gas Flow Reduces Respiratory Drive and Dyspnea in Nonintubated Venoarterial Extracorporeal Membrane Oxygenation Patients: A Pilot Study Postoperative Delirium and the Older Adult: Untangling the Confusion Failed spinal anesthesia for […]

Apixaban (Eliquis) – Guidelines+ Monographs (July 2024 Edition)

In this edition of our Guidelines+ Monographs Series, we will be taking a look at Bristol-Myers Squibb’s medication apixaban, brand name Eliquis. Initially approved in 2012, Eliquis is a factor Xa inhibitor, an anticoagulant used to prevent stroke and systemic embolism in nonvalvular atrial fibrillation, and to treat deep vein thrombosis (DVT) and pulmonary embolism […]

What's Changed - NCCN Soft Tissue Sarcoma (STS)

Soft Tissue Sarcoma – What’s Changed?

The American Cancer Society projects that in the United States alone in 2024, approximately 13,590 new cases of soft tissue sarcomas (STS) will be diagnosed, with 7,700 cases in males and 5,890 cases in females. Additionally, it is projected that about 5,200 individuals are expected to die from soft tissue sarcomas. It is important to […]

Guidelines+ Trials Spotlight - Soft Tissue Sarcoma

Soft Tissue Sarcoma – Guidelines+ Trials Rundown

Today we’re going to look at the ongoing studies and clinical trials specific to soft tissue sarcomas in adults. The below list was curated by assessing the ongoing Phase 3 trials for soft tissue sarcomas, specific to adults, and based in the United States. The dates provided are estimates, and subject to change. The list […]

ERS Int'l Guidelines

European Respiratory Society (ERS) – Guidelines International Series

Welcome to the second installment of the Guidelines International Series, where we will be delving into the European Respiratory Society (ERS). ERS stands as the largest respiratory medicine organization in Europe, with members hailing from 160 countries. As the premier membership organization for respiratory professionals, ERS is committed to advancing excellence in the study, research, […]

Guidelines Rundown - Substance Use & Mental Health

Substance Use & Mental Health – Guidelines Rundown 

We understand the critical role you play in supporting patients and communities impacted by substance use and mental health disorders. To aid your efforts, we’ve compiled a comprehensive list of essential guidelines from leading medical societies published in recent years. These guidelines are designed to enhance your practice and improve patient outcomes. Your dedication to […]

Guidelines Rundown - Soft Tissue Sarcoma (STS)

Soft Tissue Sarcoma – Guidelines Rundown

Our Guidelines Rundown Series continues with a new article dedicated to Sarcoma Awareness Month. Presently, there exists only a limited number of guidelines pertaining to Soft Tissue Sarcoma (STS), as they have only been released by a few medical societies. These guidelines offer recommendations on the management, treatment, and indications for radiation therapy for STS. […]

Guidelines Spotlight - Age-Related Hearing Loss

Age-Related Hearing Loss – Guidelines Spotlight

According to the National Institute on Deafness and Other Communication Disorders (NIDCD), age-related hearing loss (ARHL) or presbycusis is a prevalent condition among aging adults. Approximately 15% of American adults aged 18 and over report experiencing some degree of hearing difficulty, with one in three individuals between the ages of 65 and 74 experiencing hearing […]

Guidelines+ Trials Spotlight - Hemochromatosis

Advances in Hemochromatosis – Guidelines+ Trials Rundown

Today, we will explore the latest research and clinical trials focused on the management of hemochromatosis. The following list has been carefully curated by evaluating ongoing trials related to hemochromatosis in the United States. Please note that the dates provided are approximate and may be subject to change. The list primarily includes studies with results […]

Best Uses of AI LLMs in Guidelines Development

Top Ideas & Best Uses of AI / LLMs in Clinical Practice Guidelines Development

This article will examine a number of ideas and top suggestions for incorporating LLMs and AI, including Chatbots like GPT4 or Llama, into your clinical practice guidelines development process and workflows. As I’m sure you’ve heard, AI is improving and expanding rapidly, and that this is a moving target, so we’ll build upon this series […]

What's Changed & Predictions Age-Related Macular Degeneration

Age-Related Macular Degeneration Guidelines – What’s Changed Since & Guidelines Prediction Series

As the leading cause of irreversible blindness in adults 60 years of age and older, age-related macular degeneration (AMD) is a prevalent eye condition marked by central vision loss that impacts nearly 20 million individuals in the US. Despite its prevalence, afflicting approximately 1 in every 8 individuals above 60 years of age, there are […]

Guidelines Spotlight - Stimulant Use Disorder

Stimulant Use Disorder – Guidelines Spotlight

The American Society of Addiction Medicine (ASAM) and the American Academy of Addiction Psychiatry (AAAP) collaborated to develop the Clinical Practice Guideline on the Management of Stimulant Use Disorder (referred to as the Guideline). It was published on November 8, 2023. The Guideline aims to provide evidence-based strategies and clinically informed standards of care for […]

ACOG Pregnancy & Postpartum Algorithms

New Pregnancy and Postpartum Algorithms Published by ACOG

The American College of Obstetricians and Gynecologists (ACOG) and the Centers for Disease Control and Prevention (CDC) have collaborated on a multiyear initiative entitled “Identifying and Managing Obstetric Emergencies in Nonobstetric Settings.” This initiative addresses pregnancy-related emergencies and complications such as cardiomyopathy, preeclampsia, eclampsia, and stroke, as well as mental health conditions that can pose […]

AGA’s Ulcerative Colitis Guideline is Now Open for Public Comment

The American Gastroenterological Association (AGA) has announced that their latest guideline, “The AGA Living Guideline: Pharmacological Management of Moderate-To-Severe Ulcerative Colitis,” is now open for public comment. This guideline, aimed at supporting practitioners in the pharmacological management of moderate-to-severe ulcerative colitis (UC), features 14 recommendations designed to guide therapy decisions with a patient-centered approach. Referred […]

Guidelines Side-By-Side Psoriatic Arthritis

Analyzing Guidelines for Psoriatic Arthritis (PsA) – Guidelines Side-By-Side

Psoriatic arthritis (PsA) is a chronic, immune-mediated inflammatory arthritis that occurs most commonly in some people with psoriasis, a skin condition characterized by red, scaly patches. Research suggests that approximately 20-30% of people with psoriasis also develop PsA, with the majority of patient’s presenting with skin-related disease that precedes the onset of arthritis symptomatology, though […]

Guidelines Spotlight - Vitamin D for the Prevention of Disease

Vitamin D for the Prevention of Disease – Guidelines Spotlight

The Endocrine Society unveiled its latest guideline, “Vitamin D for the Prevention of Disease,” on June 3rd, 2024. This evidence-based guideline aims to establish clinical guidelines for the use of vitamin D to lower the risk of disease in individuals without established indications for vitamin D treatment or 25(OH)D testing. Recognized for its vital role […]

Upcoming FDA Approvals & Decisions - July 2024

Upcoming FDA Decisions – July 2024

The Food and Drug Administration (FDA) protects public health by guaranteeing the safety, effectiveness, and security of pharmaceuticals and medical devices. The Prescription Drug User Fee Act (PDUFA) date marks the deadline by which the FDA must complete its review of drug applications. Occasionally, an advisory committee (AdCom) meeting is convened to assess the drug […]

Guidelines + Trials Rundown - Juvenile Arthritis

Advances in Juvenile Arthritis – Guidelines+ Trials Rundown

We’re going to take a look at the ongoing studies and clinical trials specific to juvenile arthritis. The below list was curated by assessing the ongoing Phase 3 trials for juvenile arthritis that are based in the United States. The dates provided are estimates, and subject to change. The list is primarily studies that have […]

Guidelines Side-By-Side Migraine & Headache

A Comparative Analysis of Migraine & Headache Management Guidelines – National Migraine & Headache Awareness Month

National Migraine and Headache Awareness Month, observed in June, is an annual event that highlights the importance of utilizing evidence-based strategies when crafting patient-centered treatment plans for individuals grappling with headaches and migraines. With headaches ranking the 5th most common reason for emergency department visits, it is no surprise that the CDC estimates migraine disorder […]

ISTH 2024 Recap

ISTH 2024 Conference Recap – Venous Thromboembolism (VTE)

The International Society on Thrombosis and Haemostasis held its annual conference (ISTH 2024) in Bangkok, Thailand from June 22-26th. It is the premier global organization dedicated to advancing the understanding, prevention, diagnosis, and treatment of conditions related to thrombosis and hemostasis. During ISTH 2024, groundbreaking research on venous thromboembolism (VTE) was presented, showcasing the latest […]

Guidelines+ Trials Spotlight - Imfinzi® Muscle-Invasive Bladder Cancer Trial Results NIAGARA

Imfinzi® Muscle-Invasive Bladder Cancer Trial Results NIAGARA – Guidelines+ Trials Spotlight

According to the American Cancer Society, bladder cancer accounts for approximately 4% of all cancers in the United States, making it the fourth most common cancer in men and less common in women. The likelihood of men developing bladder cancer in their lifetime is about 1 in 28, while for women, the chance is about […]

Guidelines Spotlight - Epilepsy in Women

Teratogenesis, Perinatal, and Neurodevelopmental Outcomes After in Utero Exposure to Antiseizure Medication – Guidelines Spotlight

A focused guideline update “Teratogenesis, Perinatal, and Neurodevelopmental Outcomes After in Utero Exposure to Antiseizure Medication” was released by the American Academy of Neurology (AAN), the American Epilepsy Society (AES), and the Society for Maternal-Fetal Medicine (SMFM) on May 15, 2024. The new guideline updates the previous 2009 guideline for “Management Issues for Women with […]

Guidelines Side-By-Side IBS

Comparing AGA and ACG Guidelines for Irritable Bowel Syndrome (IBS) – Guidelines Side-By-Side

This week’s Guidelines Side-By-Side Series will compare the irritable bowel syndrome (IBS) guidelines from the two prominent GI-related associations in the United States – AGA and ACG. Below is an overview of the three guidelines that will be compared side-by-side. The AGA guidelines, while technically two separate documents, were published together at the same time. […]

Guidelines+ Trials Rundown - Gout

Gout in Adults – Guidelines+ Trials Rundown

Today we’re going to look at the ongoing studies and clinical trials specific to gout in adults. The below list was curated by assessing the ongoing Phase 3 trials for gout, specific for adults, and based in the United States. The dates provided are estimates, and subject to change. The list is primarily studies that […]