Treatment of Drug-Resistant Tuberculosis

Published: November 2019
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  • Key Points
  • Summary of Good Practices
  • Treatment Recommendations
    • For the selection of an effective MDR-TB treatment regimen and duration of MDR-TB treatment
    • For the selection of oral drugs for MDR-TB treatment
    • For selected oral drugs previously included in regimens for the treatment of MDR-TB
    • For the selection of drugs administered through injection when needed to compose an effective treatment regimen for MDR-TB
    • For the use of the WHO-recommended standardized shorter-course 9–12 month regimen for MDR-TB
    • For the role of surgery in the treatment of MDR-TB
    • For the treatment of isoniazid-resistant TB
    • For the management of contacts to patients with MDR-TB
  • Tables
    • Summary of Recommendations on Drugs for Use in a Treatment Regimen for Patients with MDR-TB, Including Strength of Recommendation, Certainty in the Evidence and Relative Effects on Death and Treatment Success
    • Clinical Strategy to Build an Individualized Treatment Regimen for MDR-TB
    • Doses of Drugs for Treatment of Adults and Children with MDR-TB
    • Select Antiretroviral and Non–rifamycin-based Anti-tuberculosis Drug Overlapping Toxicities and Potential Adverse Drug-drug Interactions
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The roots of the American Thoracic Society reach back to 1905, when a small group of physicians decided that the best way to improve care for tuberculosis patients was to share their experiences and discoveries. Today, the ATS has grown into an international society with more than 15,000 members. In this introductory section, you will find information about the people and programs that make the ATS the world's leading medical association dedicated to advancing our clinical and scientific understanding of pulmonary diseases, critical illnesses and sleep-related breathing disorders.



The European Respiratory Society, or ERS, is a non-profit organization with offices in Lausanne, Brussels and Sheffield.

The Infectious Diseases Society of America (IDSA) represents physicians, scientists and other health care professionals who specialize in infectious diseases. IDSA's purpose is to improve the health of individuals, communities, and society by promoting excellence in patient care, education, research, public health, and prevention relating to infectious diseases.

Description

This pocket guide attempts to define principles of practice that should produce high-quality patient care. It is applicable to specialists, primary care, and providers at all levels. This pocket guide should not be considered exclusive of other methods of care reasonably directed at obtaining the same results. The ultimate judgment concerning the propriety of any course of conduct must be made by the clinician after consideration of each individual patient situation. Neither IGC, the medical associations, nor the authors endorse any product or service associated with the distributor of this clinical reference tool.

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